Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | CCR8 | P51685 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913975 | 0.85 | TP53 (0.47) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23913807 | 0.85 | TP53 (0.47) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23914303 | 0.83 | ALDH1A1 (0.40) | MAPTSMN1; SMN2NPC1RAB9ASLC6A2 | |
| SCHEMBL23914302 | 0.83 | ALDH1A1 (0.40) | MAPTSMN1; SMN2NPC1RAB9ASLC6A2 | |
| SCHEMBL23914308 | 0.78 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP3A4KDM4E | |
| SCHEMBL23914306 | 0.78 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP3A4KDM4E | |
| SCHEMBL23914398 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP3A4KDM4E | |
| SCHEMBL23914288 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP3A4KDM4E | |
| SCHEMBL23914100 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3CYP3A4KDM4E | |
| SCHEMBL23914072 | 0.73 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317099-A1 | SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317099-A1 | SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS | MIF, LTA, MGAM | TP53 3521/4885MAPT 3922/4885SMN1; SMN2 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.