Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914375 | 0.80 | BRD4 (0.39) | KDM4EMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL14439399 | 0.80 | BRD4 (0.39) | KDM4EMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL14427628 | 0.80 | BRD4 (0.39) | KDM4EMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL10242861 | 0.73 | GRM5 (0.46) | KDM4ECYP3A4THRBTSHRTHPO | |
| SCHEMBL15676069 | 0.73 | GRM5 (0.46) | KDM4ECYP3A4THRBTSHRTHPO | |
| SCHEMBL10242864 | 0.73 | GRM5 (0.46) | KDM4ECYP3A4THRBTSHRTHPO | |
| SCHEMBL9844930 | 0.72 | CYP2A6 (0.49) | CYP3A4ALDH1A1CYP2A6CYP11B2CHRNB2 | |
| SCHEMBL15744020 | 0.71 | KDM4E (0.49) | KDM4ECYP3A4THRBTSHRTHPO | |
| SCHEMBL15744004 | 0.71 | KDM4E (0.49) | KDM4ECYP3A4THRBTSHRTHPO | |
| SCHEMBL23914102 | 0.70 | MAPT (0.44) | CYP3A4THRBTSHRMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317099-A1 | SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317099-A1 | SAFER, POTENT, AND FAST ACTING ANTIMICROBIAL AGENTS | MIF, LTA, MGAM | KDM4E 2541/4885CYP3A4 772/4885THRB 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.