SCHEMBL9844930

SCHEMBL9844930

CC1OC1c1cccnc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.49
CHRNB2 P17787 2/20 0.47
CHRNA4 P43681 2/20 0.47
CYP11B2 P19099 1/20 0.47
CYP3A4 P08684 1/20 0.45
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
CHRNA7 P36544 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA2 Q15822 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6999209 0.78 MAPT (0.49) CYP2A6CHRNB2CHRNA4CYP11B2CYP3A4
SCHEMBL23474172 0.76 CYP2A6 (0.50) CYP2A6CHRNB2CHRNA4CYP11B2CYP3A4
SCHEMBL29804975 0.74 CHRNB2 (0.56) CYP2A6CHRNB2CHRNA4CYP11B2CYP3A4
SCHEMBL18998469 0.72 CYP2A6 (0.66) CYP2A6CHRNB2CHRNA4CYP11B2ALDH1A1
SCHEMBL12143642 0.72 CYP2A6 (0.66) CYP2A6CHRNB2CHRNA4CYP11B2ALDH1A1
SCHEMBL19121445 0.72 CYP2A6 (0.66) CYP2A6CHRNB2CHRNA4CYP11B2ALDH1A1
SCHEMBL15676069 0.72 GRM5 (0.46) CHRNB2CHRNA4CYP3A4ALDH1A1LMNA
SCHEMBL10242861 0.72 GRM5 (0.46) CHRNB2CHRNA4CYP3A4ALDH1A1LMNA
SCHEMBL23914290 0.72 KDM4E (0.41) CYP2A6CHRNB2CHRNA4CYP11B2CYP3A4
SCHEMBL23758995 0.72 CYP2A6 (0.51) CYP2A6CHRNB2CHRNA4CYP11B2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0435127-A2 3-Substituted pyridines BASF Aktiengesellschaft (DE) 1991-07-03 EP claimed