Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21900387 | 0.86 | FGFR1 (0.54) | FGFR1TNFHTTTSHRCYP11B1 | |
| SCHEMBL11159254 | 0.82 | FGFR1 (0.42) | FGFR1TNFHTTADORA3ADORA2A | |
| SCHEMBL29522878 | 0.79 | DYRK1A (0.53) | FGFR1TNFHTTADORA3ADORA2A | |
| SCHEMBL2739230 | 0.79 | DYRK1A (0.53) | FGFR1TNFHTTADORA3ADORA2A | |
| SCHEMBL19911336 | 0.78 | FGFR1 (0.42) | FGFR1TNFHTTADORA3ADORA2A | |
| SCHEMBL20430443 | 0.77 | POLB (0.50) | HTTTSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19848327 | 0.76 | FGFR1 (0.41) | FGFR1TNFHTTADORA3ADORA2A | |
| SCHEMBL25975808 | 0.76 | PARP1 (0.47) | HTTALDH1A1LMNASMN1; SMN2HCAR1 | |
| SCHEMBL7732282 | 0.75 | RAB9A (0.50) | FGFR1TNFHTTADORA3ADORA2A | |
| SCHEMBL18136606 | 0.75 | NPC1 (0.50) | FGFR1TNFHTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892616-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |