Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600132 | 0.81 | L3MBTL1 (0.60) | PARP1SMN1; SMN2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL29607244 | 0.81 | L3MBTL1 (0.60) | PARP1SMN1; SMN2TP53ALDH1A1L3MBTL1 | |
| SCHEMBL24072199 | 0.79 | PARP1 (0.51) | PARP1SMN1; SMN2TP53POLBTRPA1 | |
| SCHEMBL12049203 | 0.77 | TP53 (0.53) | PARP1SMN1; SMN2TP53TRPA1ALDH1A1 | |
| SCHEMBL23915838 | 0.76 | FGFR1 (0.43) | SMN1; SMN2POLBALDH1A1L3MBTL1HCAR1 | |
| SCHEMBL31103600 | 0.74 | FGFR1 (0.59) | SMN1; SMN2TP53POLBHCAR1NPC1 | |
| SCHEMBL10084695 | 0.74 | TP53 (0.51) | SMN1; SMN2TP53POLBTRPA1ALDH1A1 | |
| SCHEMBL16181504 | 0.74 | KDM4E (0.54) | SMN1; SMN2POLBKDM4EHTTNPC1 | |
| SCHEMBL10085099 | 0.72 | HDAC6 (0.61) | SMN1; SMN2TP53POLBTRPA1ALDH1A1 | |
| SCHEMBL30704943 | 0.71 | POLB (0.48) | PARP1SMN1; SMN2TP53POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |