Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240839 | 0.80 | MTNR1A (0.57) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL30920584 | 0.79 | LOXL2 (0.76) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL22077861 | 0.79 | MTNR1A (0.59) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL23501875 | 0.79 | LOXL2 (0.76) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL11358126 | 0.76 | MTNR1A (0.60) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL4568035 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL24152675 | 0.76 | AHR (0.39) | LOXL2HRH4AHR | |
| SCHEMBL23964356 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL28929782 | 0.74 | MTNR1A (0.57) | MTNR1AMTNR1BCA2LOXL2FLT3 | |
| SCHEMBL6989977 | 0.72 | CYP1A2 (0.50) | MTNR1AMTNR1BCA2LOXL2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892616-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |