Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | GLA | P06280 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | ATM | Q13315 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.46 |
| ▸ | CASP7 | P55210 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21771607 | 0.89 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL25140697 | 0.83 | IGLV6-57 (0.49) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL24860258 | 0.80 | ALDH1A1 (0.49) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL30430934 | 0.80 | ALDH1A1 (0.53) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL12894158 | 0.76 | MAPT (0.67) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL12109476 | 0.76 | KDM4E (0.64) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL29255957 | 0.75 | KDM4E (0.66) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL24235203 | 0.75 | ALDH1A1 (0.47) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL12109485 | 0.74 | MEN1 (0.61) | MAPTKDM4EMEN1KMT2AGLA | |
| SCHEMBL8006711 | 0.73 | ALDH1A1 (0.68) | MAPTKDM4EMEN1KMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317429-A1 | METHODS AND COMPOSITIONS FOR OPTOCHEMICAL CONTROL OF CRISPR-CAS9 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317429-A1 | METHODS AND COMPOSITIONS FOR OPTOCHEMICAL CONTROL OF CRISPR-CAS9 | DCLRE1B, DNASE1, ZFR | MAPT 1287/4885KDM4E 3315/4885MEN1 4360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.