Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | SORD | Q00796 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19546959 | 0.88 | HRH4 (0.38) | HRH4ADRB1MAPTHTR3AGAA | |
| SCHEMBL19546591 | 0.83 | HRH4 (0.56) | HRH4MAPTHTR3AGAAKDM4E | |
| SCHEMBL19547082 | 0.81 | HRH4 (0.54) | HRH4ADRB1MAPTRAB9APIK3CA | |
| SCHEMBL27013486 | 0.80 | GRIN2D (0.50) | HRH4ADRB1MAPTKDM4EGRIN2D | |
| SCHEMBL16095652 | 0.80 | HRH4 (0.42) | HRH4ADRB1MAPTHTR3AGAA | |
| SCHEMBL19546973 | 0.79 | HRH3 (0.43) | HRH4MAPTKDM4EHRH3SORD | |
| SCHEMBL19546944 | 0.79 | OGA (0.40) | HRH4MAPTKDM4EL3MBTL1 | |
| SCHEMBL16333432 | 0.78 | HRH3 (0.42) | HRH4ADRB1MAPTHTR3AGAA | |
| SCHEMBL18591788 | 0.78 | ADRB1 (0.48) | HRH4ADRB1MAPTHTR3AKDM4E | |
| SCHEMBL19546962 | 0.76 | HRH3 (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892276-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AS WNT INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |