Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | SORD | Q00796 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27013486 | 0.83 | GRIN2D (0.50) | HRH4KDM4EADRB1MAPTPOLB | |
| SCHEMBL16333432 | 0.82 | HRH3 (0.42) | HRH4KDM4ERAD52UBE2NL3MBTL1 | |
| SCHEMBL18591788 | 0.82 | ADRB1 (0.48) | HRH4KDM4EL3MBTL1ADRB1MAPT | |
| SCHEMBL23916232 | 0.80 | HRH4 (0.39) | HRH4KDM4ERAD52UBE2NL3MBTL1 | |
| SCHEMBL27013483 | 0.77 | LRRK2 (0.41) | HRH4KDM4EMAPTPIK3CAHTR3A | |
| SCHEMBL24422287 | 0.77 | ME2 (0.52) | KDM4EMAPT | |
| SCHEMBL18591800 | 0.76 | HRH4 (0.37) | HRH4ADRB1PIK3CAHTR3A | |
| SCHEMBL136881 | 0.76 | PLD1 (0.56) | KDM4EMAPTPOLB | |
| SCHEMBL15228419 | 0.75 | GPR119 (0.56) | MAPTACHEPOLB | |
| SCHEMBL247930 | 0.74 | PIK3CA (0.64) | KDM4EGAAPIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151106-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |