Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966118 | 0.86 | SMN1; SMN2 (0.52) | MEN1KMT2APOLBLMNACYP1A2 | |
| SCHEMBL28626965 | 0.85 | AAK1 (0.46) | MEN1KMT2APOLBLMNACYP1A2 | |
| SCHEMBL14358948 | 0.84 | ALDH1A1 (0.43) | MEN1KMT2ALMNACYP1A2TDP1 | |
| SCHEMBL3910099 | 0.84 | MAOB (0.53) | MEN1KMT2ALMNACYP1A2MAPT | |
| SCHEMBL2795277 | 0.84 | NPC1 (0.46) | F10MEN1KMT2APOLBLMNA | |
| SCHEMBL31372038 | 0.84 | NPC1 (0.46) | F10MEN1KMT2APOLBLMNA | |
| SCHEMBL4568026 | 0.83 | MAPT (0.48) | PLAUMEN1KMT2APOLBLMNA | |
| SCHEMBL5556756 | 0.82 | AAK1 (0.46) | PLAUMEN1KMT2APOLBLMNA | |
| SCHEMBL8293053 | 0.82 | SQSTM1 (0.43) | MEN1KMT2APOLBLMNACYP1A2 | |
| SCHEMBL2111071 | 0.81 | KMT2A (0.58) | KLKB1PLAUF2F10PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892616-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |