SCHEMBL23916253

SCHEMBL23916253

Brc1cccc(Oc2cccc(N(c3ccccc3)c3ccccc3)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.46
ABCG2 Q9UNQ0 1/20 0.42
EGFR P00533 1/20 0.42
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.40
PGR P06401 1/20 0.40
CHEK1 O14757 1/20 0.40
KDR P35968 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CASP3 P42574 1/20 0.40
HTT P42858 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
LTA4H P09960 1/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
FNTA P49354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24065687 0.94 MAOB (0.41) MAOBABCG2EGFRKMT2AMAPT
SCHEMBL26233589 0.93 MAOB (0.44) MAOBABCG2EGFRKMT2AMAPT
SCHEMBL26233612 0.92 MAOB (0.42) MAOBABCG2EGFRKMT2AMAPT
SCHEMBL8943978 0.89 MAOB (0.48) MAOBKMT2AMAPTCYP1A2CYP2C9
SCHEMBL26233583 0.88 PGR (0.40) MAOBABCG2KMT2AMAPTPGR
SCHEMBL16890151 0.87 MAOB (0.47) MAOBKMT2AMAPTCYP1A2CYP2C9
SCHEMBL2623337 0.84 MAOB (0.41) MAOBKMT2AMAPTCYP1A2CYP2C9
SCHEMBL24119800 0.83 MAOB (0.44) MAOBKMT2AMAPTCYP1A2CYP2C9
SCHEMBL24119757 0.83 MAOB (0.44) MAOBKMT2AMAPTCYP1A2CYP2C9
SCHEMBL21918077 0.83 MAOB (0.44) MAOBKMT2AMAPTCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320257-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-14 US disclosed