Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.34 |
| ▸ | GSK3B | P49841 | 8/20 | 0.34 |
| ▸ | WNT1 | P04628 | 3/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.34 |
| ▸ | CLK3 | P49761 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23916726 | 0.74 | ABL1 (0.40) | ABL1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL23916234 | 0.72 | ABL1 (0.41) | ABL1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL23916169 | 0.65 | ABL1 (0.45) | ABL1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL19546601 | 0.65 | DYRK1A (0.61) | DYRK1AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL24219230 | 0.64 | DYRK1A (0.34) | ABL1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL24219758 | 0.62 | DYRK1A (0.37) | ABL1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL23740995 | 0.62 | MAP4K4 (0.34) | ABL1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL20938733 | 0.62 | NNMT (0.39) | ABL1DYRK1AGSK3BWNT1CLK2 | |
| SCHEMBL9939360 | 0.62 | ABL1 (1.00) | ABL1 | |
| SCHEMBL14511412 | 0.62 | PDPK1 (0.47) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892276-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AS WNT INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |