Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23916804 | 0.98 | TLR7 (0.39) | TLR7TLR8KDM4EALDH1A1GAA | |
| SCHEMBL23917096 | 0.94 | KDM4E (0.39) | TLR7TLR8KDM4EALDH1A1GAA | |
| SCHEMBL23917076 | 0.88 | TLR7 (0.40) | TLR7TLR8KDM4EALDH1A1GAA | |
| SCHEMBL23916790 | 0.85 | TLR7 (0.40) | TLR7TLR8KDM4EALDH1A1GAA | |
| SCHEMBL23917058 | 0.81 | TLR7 (0.39) | TLR7TLR8KDM4EALDH1A1GAA | |
| SCHEMBL29315205 | 0.79 | KDM4E (0.40) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL23916913 | 0.78 | TLR7 (0.36) | TLR7TLR8NLRP3 | |
| SCHEMBL29314869 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL29315208 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1GAAHSD17B10GLA | |
| SCHEMBL29314714 | 0.76 | DRD4 (0.39) | TLR7TLR8KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317118-A1 | NLRP3 MODULATORS | INNATE TUMOR IMMUNITY INC (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317118-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, PYCARD | TLR7 236/4885TLR8 210/4885KDM4E 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.