PYCARD

Apoptosis-associated speck-like protein containing a CARD · Q9ULZ3 · PYCARD on Sugi Atlas →

0 patent compounds predicted against PYCARD, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PYCARD by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Colchicine for Symptom and Inflammation in Knee Osteoarthritis PHASE2/PHASE3COMPLETED
Disulfiram in Rheumatoid Arthritis PHASE2NOT_YET_RECRUITING
Effect of Periodontal Treatment on Inflammasome Proteins in Periodontal Diseases nanUNKNOWN
Characterization of Non-canonical Way in Inflammasome Monocytes of Patients With Severe Sepsis nanCOMPLETED
Evaluation of Inflammasome Gene Polymorphisms in Periodontitis Patients nanUNKNOWN
Inflammasomes in Cell Death in FTMH, ERM, and RRD nanCOMPLETED
New Signaling Pathway Targeting Systemic Lupus Erythematosus nanUNKNOWN
Role of Type 2 Diabetes in Potentiating the Inflammatory Response Post Extracorporeal Circulation After Cardiac Surgery nanWITHDRAWN
Effect of Low Dose of Colchicine on Platelet Reactivity nanCOMPLETED
Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients nanUNKNOWN
Role NLRP3 Inflammasome in Weight Loss Following Sleeve Gastrectomy in Morbidly Obese Patients nanUNKNOWN
Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1 nanUNKNOWN
Gluten-related Disorders in Familial Mediterranean Fever Patients nanCOMPLETED
The Mechanisms and Significances of Synergistic Effects of Mycophenolic Acid and LPS on IL-1β Secretion by Mononuclear nanUNKNOWN
Probiotics and Systemic Inflammation in Patients With Metabolic Syndrome and High Cardiovascular Risk nanWITHDRAWN
Nucleotide Protein -3 in Epileptic Children nanUNKNOWN
Potential Role of Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients: Impact of Ferretin and D -Dimer. nanUNKNOWN
The T Cell Activator of Cell Killing (TACK) IT ON STUDY nanRECRUITING
Establishment of Genomic, Transcriptomic and Functional Characteristics of Tumor Cells in Hyperinflammatory Hemopathies nanNOT_YET_RECRUITING
TRPM2 Gene Polymorphism, NLRP3 Inflammasome Expression in Vitiligo Patients nanACTIVE_NOT_RECRUITING
The Role of Pyroptosis in Chronic Venous Disease nanUNKNOWN
Health-related Quality of Life, Electrocardiographic and Holter Findings in Children With Familial Mediterranean Fever nanACTIVE_NOT_RECRUITING
Extremes of Coronary Artery Disease and Normality:CAD Extremes nanRECRUITING
Suppression of Postprandial Monocyte Activation by Blueberries or Docosahexaenoic Acid in Humans nanCOMPLETED
Caspase-1 Activity, IL-1beta, and IL-18 in Patients With FMF nanNOT_YET_RECRUITING
(NOD)-Like Receptors CARD Domain-Containing 4 Levels in Individuals With Periodontitis nanUNKNOWN
Macrolide Mediates Pulmonary Infection of Pseudomonas Aeruginosa nanCOMPLETED
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective nanCOMPLETED
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Activation of a Cutaneous Inflammasome in the Skin of Hidradenitis Suppurativa Patients nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PYCARD binder may also engage these)

ProteinNameSimilarity
Q9EPB4 1.000 Q9EPB4 →
Q8HXK9 0.991 Q8HXK9 →
Q8WXC3 0.983 Q8WXC3 →
Q9I9N6 0.969 Q9I9N6 →
Q6GZR1 0.969 Q6GZR1 →
CASP9 Caspase-9 0.966 landscape →
Q2KI74 0.965 Q2KI74 →
Q66674 0.964 Q66674 →
Q9I9N5 0.963 Q9I9N5 →
Q645M6 0.963 Q645M6 →
Q1M161 0.962 Q1M161 →
Q8VDP3 0.962 Q8VDP3 →
Q3U0V2 0.962 Q3U0V2 →
Q8TE68 0.962 Q8TE68 →
F5HEZ4 0.961 F5HEZ4 →
Q5RC07 0.961 Q5RC07 →
D3ZBP4 0.961 D3ZBP4 →
O09127 0.961 O09127 →
Q9H6S3 0.960 Q9H6S3 →
ARHGEF1 Rho guanine nucleotide exchange factor 1 0.959 landscape →
P98150 0.959 P98150 →
Q9Z1I6 0.959 Q9Z1I6 →
EPHB4 Ephrin type-B receptor 4 0.958 landscape →
P25799 0.958 P25799 →
A5PK26 0.958 A5PK26 →
Q15027 0.958 Q15027 →
Q5RCH4 0.958 Q5RCH4 →
Q8BYG9 0.958 Q8BYG9 →
NFKB2 Nuclear factor NF-kappa-B p100 subunit 0.958 landscape →
Q640S6 0.957 Q640S6 →