SCHEMBL23916959

SCHEMBL23916959

c1ccc2cc3c(cc2c1)sc1cc2c(cc13)sc1cc3c(cc12)sc1ccccc13

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.61
ALDH1A1 P00352 7/20 0.53
MAPT P10636 5/20 0.53
RAB9A P51151 3/20 0.53
HPGD P15428 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
POLB P06746 1/20 0.45
PTPN7 P35236 1/20 0.41
DUSP3 P51452 1/20 0.41
PTPN12 Q05209 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41
CYP1A2 P05177 1/20 0.40
KDM4E B2RXH2 3/20 0.40
NPC1 O15118 1/20 0.40
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA12 O43570 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17228832 1.00 GPR3 (0.61) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL2742087 0.98 GPR3 (0.64) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL29450187 0.98 GPR3 (0.64) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL2336137 0.94 GPR3 (0.58) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL23916960 0.93 GPR3 (0.64) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL23513821 0.91 GPR3 (0.67) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL23513817 0.91 GPR3 (0.67) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL752667 0.91 GPR3 (0.43) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL14925146 0.89 GPR3 (0.48) GPR3ALDH1A1MAPTRAB9AHPGD
SCHEMBL1637414 0.89 GPR3 (0.78) GPR3ALDH1A1MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320266-A1 FUSED HETERO 5-MEMBERED RING MOLECULE, p-TYPE SEMICONDUCTOR FILM AND ELECTRONIC DEVICE PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320266-A1 FUSED HETERO 5-MEMBERED RING MOLECULE, p-TYPE SEMICONDUCTOR FILM AND ELECTRONIC DEVICE TST, BMI1, SLC7A5 GPR3 3903/4885ALDH1A1 3957/4885MAPT 2494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.