Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 4/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | ABL2 | P42684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917520 | 0.81 | KDR (0.38) | LIMK1CSF1RSRCEGFRPIK3CG | |
| SCHEMBL8820858 | 0.78 | SRC (0.54) | LIMK1SRCEGFRCDK1ESR1 | |
| SCHEMBL8820707 | 0.73 | LIMK1 (0.37) | LIMK1CSF1RSRCEGFRCDK1 | |
| SCHEMBL8820698 | 0.73 | LIMK1 (0.37) | LIMK1CSF1RSRCEGFRCDK1 | |
| SCHEMBL8820827 | 0.71 | SRC (0.55) | LIMK1SRCEGFRCDK1ADORA3 | |
| SCHEMBL3490619 | 0.71 | LIMK1 (0.44) | LIMK1ADORA3ADORA2AADORA1PI4KA | |
| SCHEMBL13193105 | 0.70 | CSF1R (0.70) | CSF1RKDR | |
| SCHEMBL16655699 | 0.69 | PIK3CD (0.42) | LIMK1CSF1RSRCEGFRCDK1 | |
| SCHEMBL28474962 | 0.69 | LIMK1 (0.39) | LIMK1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8820773 | 0.67 | PIK3CD (0.41) | LIMK1SRCEGFRCDK1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | LIMK1 395/4885CSF1R 2312/4885SRC 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.