Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 8/20 | 0.35 |
| ▸ | EGFR | P00533 | 6/20 | 0.34 |
| ▸ | ABL1 | P00519 | 5/20 | 0.34 |
| ▸ | ABL2 | P42684 | 5/20 | 0.34 |
| ▸ | CDK1 | P06493 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CSK | P41240 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819671 | 0.88 | EGFR (0.42) | LIMK1SRCEGFRABL1ABL2 | |
| SCHEMBL8819680 | 0.87 | SRC (0.36) | LIMK1CSF1RSRCEGFRABL1 | |
| SCHEMBL8819471 | 0.85 | PI4KA (0.46) | CSF1RSRCEGFRABL1ABL2 | |
| SCHEMBL8819661 | 0.84 | SRC (0.38) | LIMK1CSF1RSRCEGFRABL1 | |
| SCHEMBL8819502 | 0.80 | PI4KA (0.47) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL8819716 | 0.78 | PI4KA (0.48) | LIMK1SRCEGFRABL1ABL2 | |
| SCHEMBL8820521 | 0.77 | PI4KA (0.46) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL8820858 | 0.77 | SRC (0.54) | LIMK1SRCEGFRABL1ABL2 | |
| SCHEMBL8819945 | 0.76 | MAPT (0.36) | SRCEGFRABL1ABL2KDR | |
| SCHEMBL8819676 | 0.76 | PI4KA (0.47) | SRCEGFRABL1ABL2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | disclosed |