SCHEMBL23917310

SCHEMBL23917310

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c6nc7ccccn7c6ccc54)c(-c4ccccc4)c3)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.31
ALDH1A1 P00352 4/20 0.31
GLA P06280 4/20 0.31
GAA P10253 4/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PARP1 P09874 1/20 0.31
POLB P06746 2/20 0.30
HPGD P15428 2/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA3 P34903 1/20 0.30
GABRA2 P47869 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21622690 0.87 TDO2 (0.38) KDM4EALDH1A1GLAGAANPC1
SCHEMBL23917140 0.85 KDM4E (0.36) KDM4EALDH1A1GLAGAANPC1
SCHEMBL20177054 0.80 L3MBTL1 (0.41) KDM4EALDH1A1NPC1RAB9AHPGD
SCHEMBL20277185 0.80 MEN1 (0.39) KDM4EALDH1A1GLAPOLBHPGD
SCHEMBL25799991 0.78 MEN1 (0.33) ALDH1A1POLBHPGDMEN1MAPT
SCHEMBL24603977 0.78 MEN1 (0.33) ALDH1A1POLBHPGDMEN1MAPT
SCHEMBL24603899 0.78 MEN1 (0.31) KDM4EALDH1A1GLAHPGDMEN1
SCHEMBL25800880 0.78 MEN1 (0.31) KDM4EALDH1A1GLAHPGDMEN1
SCHEMBL21147778 0.77 MEN1 (0.37) KDM4EALDH1A1GLAPOLBHPGD
SCHEMBL23676941 0.77 MEN1 (0.33) KDM4EALDH1A1GLASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581497-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 US disclosed
EP-3820966-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-08 EP disclosed
US-20210320264-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11581497-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM KDM4E 2132/4885ALDH1A1 504/4885GLA 1843/4885
US-20210320264-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM KDM4E 2132/4885ALDH1A1 504/4885GLA 1843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.