Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917073 | 0.88 | NPC1 (0.36) | NPC1RAB9AADRA1BNTRK1KDM4E | |
| SCHEMBL21622982 | 0.87 | ALDH1A1 (0.43) | NPC1RAB9AADRA1BNTRK1KDM4E | |
| SCHEMBL18026430 | 0.85 | MAPT (0.37) | KDM4EALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL23917140 | 0.82 | KDM4E (0.36) | NPC1RAB9AADRA1BNTRK1KDM4E | |
| SCHEMBL23917128 | 0.82 | KDM4E (0.37) | NPC1RAB9AADRA1BNTRK1KDM4E | |
| SCHEMBL23917145 | 0.82 | KDM4E (0.39) | NPC1RAB9AADRA1BNTRK1KDM4E | |
| SCHEMBL23917309 | 0.82 | KDM4E (0.39) | NPC1RAB9AADRA1BNTRK1KDM4E | |
| SCHEMBL22211857 | 0.82 | ALDH1A1 (0.35) | KDM4EALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL22133345 | 0.82 | L3MBTL1 (0.40) | KDM4EALDH1A1HPGDMAPTNPSR1 | |
| SCHEMBL18026397 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-02-14 | — | — | US | disclosed |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | NPC1 3299/4885RAB9A 2729/4885ADRA1B 4239/4885 |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | NPC1 3299/4885RAB9A 2729/4885ADRA1B 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.