Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.36 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917364 | 0.90 | KDM4E (0.49) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL21622934 | 0.87 | KDM4E (0.44) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL23917311 | 0.86 | KDM4E (0.43) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL21364447 | 0.85 | ADORA2A (0.46) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL21622725 | 0.83 | ALDH1A1 (0.39) | KDM4EL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21622927 | 0.79 | KDM4E (0.42) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL23917082 | 0.77 | ALDH1A1 (0.47) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL22649088 | 0.76 | KDM4E (0.45) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL23917394 | 0.76 | KDM4E (0.45) | KDM4EL3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23917067 | 0.75 | KDM4E (0.47) | KDM4EL3MBTL1ATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-02-14 | — | — | US | disclosed |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | KDM4E 2132/4885L3MBTL1 1397/4885ATM 3016/4885 |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | KDM4E 2132/4885L3MBTL1 1397/4885ATM 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.