Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917364 | 0.79 | KDM4E (0.49) | KDM4EL3MBTL1ADORA2AHPGDLMNA | |
| SCHEMBL12014898 | 0.79 | KDM4E (0.56) | KDM4EL3MBTL1CYP19A1HPGDLMNA | |
| SCHEMBL21622927 | 0.79 | KDM4E (0.42) | KDM4EL3MBTL1ADORA2AHPGDLMNA | |
| SCHEMBL23917082 | 0.77 | ALDH1A1 (0.47) | KDM4EL3MBTL1ADORA2AHPGDLMNA | |
| SCHEMBL23917319 | 0.76 | KDM4E (0.41) | KDM4EL3MBTL1ADORA2AHPGDLMNA | |
| SCHEMBL21364436 | 0.76 | ADORA2A (0.42) | KDM4EL3MBTL1ADORA2AHPGDLMNA | |
| SCHEMBL21622934 | 0.75 | KDM4E (0.44) | KDM4EL3MBTL1ADORA2AHPGDLMNA | |
| SCHEMBL23917304 | 0.75 | KDM4E (0.36) | KDM4EL3MBTL1ADORA2AHPGDLMNA | |
| SCHEMBL21622931 | 0.74 | POLB (0.33) | KDM4EL3MBTL1HPGDLMNAALDH1A1 | |
| SCHEMBL23917311 | 0.74 | KDM4E (0.43) | KDM4EL3MBTL1ADORA2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-02-14 | — | — | US | disclosed |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | KDM4E 2132/4885L3MBTL1 1397/4885CYP19A1 3203/4885 |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | KDM4E 2132/4885L3MBTL1 1397/4885CYP19A1 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.