Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21658642 | 0.83 | — | — | |
| SCHEMBL19738891 | 0.80 | TRPA1 (0.32) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20998431 | 0.77 | — | — | |
| SCHEMBL13625560 | 0.77 | — | — | |
| SCHEMBL9492556 | 0.77 | — | — | |
| SCHEMBL20077710 | 0.77 | — | — | |
| SCHEMBL308456 | 0.77 | — | — | |
| SCHEMBL20387888 | 0.76 | — | — | |
| SCHEMBL16803975 | 0.75 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12677909 | 0.75 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192961-A2 | LIGAND-PAYLOAD CONJUGATES | PYXIS ONCOLOGY, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| EP-3892305-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | Sutro Biopharma, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |