Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911519 | 0.89 | PGR (0.46) | PGRADORA3PTGS1SLC6A2CYP1A2 | |
| SCHEMBL25597388 | 0.85 | CYP1A2 (0.39) | PGRADORA3PTGS1SLC6A2CYP1A2 | |
| SCHEMBL2352782 | 0.83 | GRIN2D (0.55) | CYP1A2CYP2C19ALDH1A1CYP2D6MAPT | |
| SCHEMBL104860 | 0.79 | GRIN2D (0.55) | PGRADORA3PTGS1SLC6A2CYP1A2 | |
| SCHEMBL20889860 | 0.79 | HSD17B10 (0.36) | PGRADORA3PTGS1SLC6A2CYP1A2 | |
| SCHEMBL2736162 | 0.78 | ALDH1A1 (0.53) | PGRADORA3PTGS1SLC6A2ALDH1A1 | |
| SCHEMBL19248854 | 0.78 | CYP1A2 (0.49) | PGRADORA3PTGS1SLC6A2CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL5620498 | 0.77 | GRIN2D (0.53) | PGRADORA3PTGS1SLC6A2CYP1A2 | |
| Hydrochloric Acid SCHEMBL28948556 | 0.77 | GRIN2D (0.53) | PGRADORA3PTGS1SLC6A2CYP1A2 | |
| SCHEMBL22000551 | 0.77 | CYP1A2 (0.40) | PGRADORA3PTGS1SLC6A2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317103-A1 | ASK1 INHIBITING AGENTS | BIOGEN MA INC. | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317103-A1 | ASK1 INHIBITING AGENTS | MAP3K1, MAP3K6, MAP3K10 | PGR 2995/4885ADORA3 3715/4885PTGS1 1147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.