SCHEMBL23917847

SCHEMBL23917847

CCc1ccc(C(=O)c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.50
CNR1 P21554 2/20 0.50
CNR2 P34972 2/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
HTT P42858 1/20 0.50
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 1/20 0.49
RAB9A P51151 4/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
USP5 P45974 1/20 0.49
PLK1 P53350 1/20 0.48
NPC1 O15118 4/20 0.45
GAA P10253 2/20 0.45
POLB P06746 1/20 0.45
AGTR1 P30556 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148332 0.85 CNR1 (0.58) ALDH1A1SMN1; SMN2CNR1CNR2LMNA
SCHEMBL2935942 0.85 ALDH1A1 (0.70) ALDH1A1SMN1; SMN2CNR1CNR2LMNA
Hydrogen Peroxide SCHEMBL6280050 0.83 L3MBTL1 (0.52) ALDH1A1CNR2LMNAHTTCYP2C9
SCHEMBL139408 0.83 L3MBTL1 (0.56) ALDH1A1LMNARAB9ANPC1L3MBTL1
SCHEMBL11118356 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2CNR1CNR2LMNA
SCHEMBL28399335 0.80 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2CNR1CNR2LMNA
SCHEMBL28415302 0.79 CNR1 (0.57) ALDH1A1SMN1; SMN2CNR1CNR2LMNA
Alcohol SCHEMBL11354975 0.78 USP5 (0.46) ALDH1A1SMN1; SMN2CNR1CNR2LMNA
SCHEMBL50522 0.78 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CNR1CNR2LMNA
SCHEMBL975055 0.78 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037453-B2 Aromatic polyethers containing a biosourced furan diol ROQUETTE FRERES (FR) 2024-07-16 US disclosed
US-20210317265-A1 AROMATIC POLYETHERS CONTAINING A BIOSOURCED FURAN DIOL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-10-14 US disclosed