Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26416381 | 0.78 | PTPN2 (0.42) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL21250753 | 0.75 | PDGFRB (0.46) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL28331891 | 0.72 | PTPN2 (0.38) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL30353863 | 0.70 | GAA (0.62) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL1049325 | 0.70 | GAA (0.62) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL19425817 | 0.69 | PDGFRB (0.42) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL31324048 | 0.69 | PDGFRB (0.42) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL4163870 | 0.69 | PDGFRB (0.42) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL29765639 | 0.69 | PDGFRB (0.42) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL1412726 | 0.69 | PDGFRB (0.42) | PTPN2PTPN1PDGFRBGPR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317153-A1 | IRIDIUM (III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR USE THEREOF IN CANCER TREATMENT | THE UNIVERSITY OF HONG KONG (HK) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317153-A1 | IRIDIUM (III) COMPLEXES CONTAINING N-HETEROCYCLIC CARBENE LIGAND, SYNTHESIS, AND THEIR USE THEREOF IN CANCER TREATMENT | HCCS, CASP3, BAD | PTPN2 3823/4885PTPN1 3658/4885PDGFRB 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.