Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28138831 | 0.82 | PTPN2 (0.35) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL28331891 | 0.79 | PTPN2 (0.38) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL28138899 | 0.78 | BRD4 (0.40) | LMNAALDH1A1ALOX12HTT | |
| SCHEMBL23917940 | 0.78 | PTPN2 (0.44) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL28138322 | 0.77 | PTPN2 (0.32) | PTPN2PTPN1GPR3 | |
| SCHEMBL28138887 | 0.77 | PTPN2 (0.32) | PTPN2PTPN1GPR3 | |
| SCHEMBL28138835 | 0.74 | BRD4 (0.37) | LMNAALDH1A1ALOX12HTT | |
| SCHEMBL21250753 | 0.73 | PDGFRB (0.46) | PTPN2PTPN1PDGFRBGPR3LMNA | |
| SCHEMBL28138290 | 0.73 | PTPN2 (0.34) | PTPN2PTPN1PDGFRB | |
| SCHEMBL28138284 | 0.73 | PTPN2 (0.34) | PTPN2PTPN1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125434-A1 | METHOD FOR PRODUCING MONOSULFOXIDE DERIVATIVE | KUMIAI CHEMICAL INDUSTRY CO. LTD. (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230125434-A1 | METHOD FOR PRODUCING MONOSULFOXIDE DERIVATIVE | TST, STS, MPST | PTPN2 1113/4885PTPN1 1590/4885PDGFRB 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.