Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 7/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635018 | 1.00 | HRH3 (0.46) | HRH3SIGMAR1TSHRNUAK1MAOB | |
| SCHEMBL23635017 | 1.00 | HRH3 (0.46) | HRH3SIGMAR1TSHRNUAK1MAOB | |
| SCHEMBL23634917 | 0.96 | SIGMAR1 (0.46) | HRH3SIGMAR1MAOBACHEMAOA | |
| SCHEMBL23634842 | 0.96 | SIGMAR1 (0.46) | HRH3SIGMAR1MAOBACHEMAOA | |
| SCHEMBL23634900 | 0.96 | SIGMAR1 (0.46) | HRH3SIGMAR1MAOBACHEMAOA | |
| SCHEMBL23635015 | 0.93 | DDB1 (0.46) | SIGMAR1ACHEBCHE | |
| SCHEMBL23635043 | 0.93 | SIGMAR1 (0.48) | HRH3SIGMAR1TSHRNUAK1MAOB | |
| SCHEMBL23634899 | 0.93 | SIGMAR1 (0.48) | HRH3SIGMAR1TSHRNUAK1MAOB | |
| SCHEMBL23635019 | 0.93 | DDB1 (0.46) | SIGMAR1ACHEBCHE | |
| SCHEMBL23635016 | 0.93 | DDB1 (0.46) | SIGMAR1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317109-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317109-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | CRBN, CLNS1A, ADRM1 | HRH3 3065/4885SIGMAR1 3610/4885TSHR 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.