SCHEMBL23919110

SCHEMBL23919110

Cc1cc2cc3occ(C)c3cc2o1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
KDM4E B2RXH2 6/20 0.47
MAOA P21397 1/20 0.42
HPGD P15428 4/20 0.41
HSD17B10 Q99714 3/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 2/20 0.39
KCNA3 P22001 5/20 0.38
KCNA2 P16389 1/20 0.38
KCNA1 Q09470 1/20 0.38
ALDH1A2 O94788 1/20 0.38
ALDH2 P05091 1/20 0.38
ALDH1B1 P30837 1/20 0.38
ALDH1A3 P47895 1/20 0.38
CYP3A4 P08684 2/20 0.36
CYP1A1 P04798 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.36
DYRK1A Q13627 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19248240 0.81 ALDH1A1 (0.57) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL9961317 0.78 DYRK1A (0.47) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL21166571 0.77 DYRK1A (0.40) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL25165205 0.74 DYRK1A (0.44) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL19248241 0.74 ALDH1A1 (0.67) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL23919117 0.72 KCNA3 (0.46) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL862531 0.72 DYRK1A (0.42) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL8404362 0.72 ALDH1A1 (0.53) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL4419972 0.71 DYRK1A (0.45) ALDH1A1KDM4EMAOAHPGDHSD17B10
SCHEMBL18177588 0.71 PIM1 (0.44) ALDH1A1KDM4EMAOAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301185-A1 COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-21 US disclosed
US-20230301185-A1 COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-21 US disclosed
US-11319330-B2 Tricyclic furan-substituted piperidinedione compound MEDSHINE DISCOVERY INC. (CN) 2022-05-03 US disclosed
US-20210317138-A1 TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND MEDSHINE DISCOVERY INC. (CN) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319330-B2 Tricyclic furan-substituted piperidinedione compound CRBN, PFDN1, CLNS1A ALDH1A1 2383/4885KDM4E 2404/4885MAOA 3329/4885
US-20210317138-A1 TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND CRBN, PFDN1, CLNS1A ALDH1A1 2383/4885KDM4E 2404/4885MAOA 3329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.