Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19248240 | 0.79 | ALDH1A1 (0.57) | KCNA3ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL12277880 | 0.78 | ALDH1A1 (0.44) | KCNA3ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL12277950 | 0.78 | ALDH1A1 (0.49) | KCNA3ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL19248241 | 0.77 | ALDH1A1 (0.67) | KCNA3ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL30360776 | 0.75 | CYP2A6 (0.37) | ALDH1A1KDM4EHPGDPOLBCYP3A4 | |
| SCHEMBL28592231 | 0.75 | CYP2A6 (0.37) | ALDH1A1KDM4EHPGDPOLBCYP3A4 | |
| SCHEMBL8404362 | 0.75 | ALDH1A1 (0.53) | KCNA3ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL12183 | 0.73 | MAOB (0.44) | KCNA3CYP1A2MAOA | |
| SCHEMBL12278544 | 0.72 | ALDH1A1 (0.41) | KCNA3ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL23919110 | 0.72 | ALDH1A1 (0.47) | KCNA3ALDH1A1KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319330-B2 | Tricyclic furan-substituted piperidinedione compound | MEDSHINE DISCOVERY INC. (CN) | 2022-05-03 | — | — | US | disclosed |
| US-20210317138-A1 | TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319330-B2 | Tricyclic furan-substituted piperidinedione compound | CRBN, PFDN1, CLNS1A | KCNA3 4073/4885ALDH1A1 2383/4885KDM4E 2404/4885 |
| US-20210317138-A1 | TRICYCLIC FURAN-SUBSTITUTED PIPERIDINEDIONE COMPOUND | CRBN, PFDN1, CLNS1A | KCNA3 4073/4885ALDH1A1 2383/4885KDM4E 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.