Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003924 | 0.88 | MKNK1 (0.56) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 | |
| SCHEMBL12413787 | 0.82 | MKNK1 (0.61) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 | |
| SCHEMBL18934268 | 0.82 | TDP1 (0.51) | CYP2D6ALDH1A1CYP1A2 | |
| SCHEMBL10720375 | 0.82 | SIGMAR1 (0.46) | — | |
| SCHEMBL23514716 | 0.81 | CYP2A6 (0.59) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 | |
| SCHEMBL13878057 | 0.80 | CYP2A6 (0.67) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 | |
| SCHEMBL8340357 | 0.80 | CYP2A6 (0.57) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 | |
| SCHEMBL16068455 | 0.77 | CYP2A6 (0.62) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 | |
| SCHEMBL1622170 | 0.77 | CYP2A6 (0.67) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 | |
| SCHEMBL20732513 | 0.75 | CYP3A4 (0.49) | CYP2A6MKNK1MKNK2CYP3A4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315876-A1 | METHODS FOR REVERSING HIV LATENCY USING BAF COMPLEX MODULATING COMPOUNDS | PURDUE RESEARCH FOUNDATION | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315876-A1 | METHODS FOR REVERSING HIV LATENCY USING BAF COMPLEX MODULATING COMPOUNDS | CHD1L, SMARCC1, CHD1 | CYP2A6 3991/4885MKNK1 2135/4885MKNK2 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.