Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18306023 | 0.87 | ATM (0.54) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL1642668 | 0.85 | ATM (0.51) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL12906609 | 0.84 | ATM (0.61) | ATMPRTN3CTSKCTSLCTSS | |
| SCHEMBL7202123 | 0.83 | ATM (0.54) | ATMPRTN3CTSKCTSLCTSS | |
| SCHEMBL7202125 | 0.83 | ATM (0.54) | ATMPRTN3CTSKCTSLCTSS | |
| SCHEMBL8410322 | 0.82 | ELANE (0.49) | ATMPRTN3CTSKCTSLCTSS | |
| SCHEMBL11785122 | 0.80 | CTSL (0.60) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL12330615 | 0.80 | CTSL (0.57) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL5704553 | 0.80 | CTSL (0.53) | ATMPRTN3CTSKCTSLCTSS | |
| SCHEMBL2392485 | 0.79 | ATM (0.47) | ATMPRTN3CTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013008-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |