Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642419 | 0.88 | SYK (0.47) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL18157219 | 0.82 | ATM (0.53) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL3276084 | 0.80 | ATM (0.49) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL2391978 | 0.79 | ATM (0.52) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL2392482 | 0.79 | ATM (0.46) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL9789172 | 0.78 | SYK (0.47) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL23455707 | 0.77 | ATM (0.53) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL6487029 | 0.77 | ATM (0.53) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL17352430 | 0.77 | ATM (0.53) | ATMSYKCTSKCTSLCTSB | |
| SCHEMBL23455705 | 0.77 | ATM (0.53) | ATMSYKCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013008-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |