Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 9/20 | 0.71 |
| ▸ | MET | P08581 | 2/20 | 0.67 |
| ▸ | KDR | P35968 | 2/20 | 0.67 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331893 | 0.88 | PIM1 (0.56) | PIM1METKDRBIRC5MAPT | |
| SCHEMBL29331950 | 0.87 | PIM1 (0.69) | PIM1METKDRMAPTKDM4E | |
| SCHEMBL29332771 | 0.83 | GSK3B (0.55) | PIM1METKDRMAPTKDM4E | |
| SCHEMBL2071066 | 0.76 | PIM1 (0.77) | PIM1METKDRBIRC5MAPT | |
| SCHEMBL23841109 | 0.73 | ATM (0.72) | PIM1METKDRBIRC5KDM4E | |
| SCHEMBL31695310 | 0.73 | KMT2A (0.63) | PIM1METKDRBIRC5MAPT | |
| SCHEMBL2201383 | 0.72 | PIM1 (0.55) | PIM1METKDRMAPTKDM4E | |
| SCHEMBL2203770 | 0.71 | MEN1 (0.56) | PIM1METKDRMAPTKDM4E | |
| SCHEMBL29334503 | 0.71 | PIM1 (0.67) | PIM1METKDRBIRC5MAPT | |
| SCHEMBL8535730 | 0.71 | KDM4E (0.59) | PIM1METKDRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317114-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 | TRUSTEES OF BOSTON UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317114-A1 | SMALL MOLECULE INHIBITORS OF INTERLEUKIN-4 | IL4, IL2, IL4I1 | PIM1 319/4885MET 625/4885KDR 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.