SCHEMBL23920388

SCHEMBL23920388

c1ccc(-c2ccc3cc(-c4nc(-c5ccc6ccccc6c5)nc(-c5ccc6sc7ccccc7c6c5)n4)ccc3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM3 Q86V86 1/20 0.42
ESR1 P03372 3/20 0.40
ESR2 Q92731 3/20 0.40
CYP1A2 P05177 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
LIMK1 P53667 1/20 0.40
GPR3 P46089 1/20 0.40
CYP17A1 P05093 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
ROCK1 Q13464 1/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21109065 0.99 CYP1A2 (0.42) PIM3ESR1ESR2CYP1A2KDM4E
SCHEMBL17693932 0.99 CYP1A2 (0.42) PIM3ESR1ESR2CYP1A2KDM4E
SCHEMBL15501661 0.97 CYP1A2 (0.43) PIM3ESR1ESR2CYP1A2KDM4E
SCHEMBL15501382 0.97 CYP1A2 (0.43) PIM3ESR1ESR2CYP1A2KDM4E
SCHEMBL23633532 0.97 CYP1A2 (0.43) PIM3ESR1ESR2CYP1A2KDM4E
SCHEMBL25817921 0.96 PIM3 (0.40) PIM3ESR1ESR2CYP1A2KDM4E
SCHEMBL24266731 0.96 GPR3 (0.41) PIM3ESR1ESR2CYP1A2KDM4E
SCHEMBL15501879 0.96 SMN1; SMN2 (0.44) PIM3CYP1A2KDM4EMEN1ALDH1A1
SCHEMBL27252325 0.94 CYP1A2 (0.41) PIM3CYP1A2KDM4EMEN1ALDH1A1
SCHEMBL25817725 0.94 HSD17B1 (0.41) PIM3ESR1ESR2CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320263-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-14 US disclosed