SCHEMBL23920989

SCHEMBL23920989

COCCNC(=O)CSc1nc2c(=O)[nH]c(N)nc2n1CCO

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
PNP P00491 2/20 0.44
PKM P14618 1/20 0.44
MAPK1 P28482 1/20 0.44
POLB P06746 2/20 0.43
ALDH1A1 P00352 8/20 0.42
MAPT P10636 1/20 0.42
GAA P10253 3/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 3/20 0.41
TSHR P16473 1/20 0.41
USP2 O75604 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23920837 0.91 PNP (0.43) ATMPNPPKMMAPK1POLB
SCHEMBL23921227 0.89 ALDH1A1 (0.47) PNPALDH1A1MAPTKDM4ETSHR
SCHEMBL23921077 0.88 PNP (0.41) ATMPNPPOLBMAPTGAA
SCHEMBL23921107 0.85 PNP (0.47) PNPMAPK1POLBALDH1A1GAA
SCHEMBL21396481 0.84 MEN1 (0.44) ATMPNPMAPK1POLBALDH1A1
SCHEMBL23920922 0.84 PNP (0.38) ATMPNPMAPK1ALDH1A1MAPT
SCHEMBL25928193 0.82 PNP (0.37) PNPALDH1A1MAPTGAAKDM4E
SCHEMBL21396435 0.82 PNP (0.42) PNPMAPK1ALDH1A1HPGDTSHR
SCHEMBL23921094 0.80 PNP (0.48) PNPALDH1A1HPGDTSHRUSP2
SCHEMBL21396394 0.80 PNP (0.51) PNPALDH1A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2023-08-03 US disclosed
US-20210317156-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES MIRECA MEDICINES GMBH (DE) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242568-A1 POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PRKAG3 ATM 1507/4885PNP 111/4885PKM 249/4885
US-20210317156-A1 NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES PRKG1, PRKG2, PDE7A ATM 1565/4885PNP 106/4885PKM 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.