Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909175 | 0.79 | MEN1 (0.52) | KMT2AMEN1FAAHMAPK1TSHR | |
| SCHEMBL23772388 | 0.79 | MEN1 (0.55) | KMT2AMEN1FAAHMAPK1TSHR | |
| SCHEMBL25162239 | 0.77 | TSHR (0.41) | KMT2AMEN1FAAHMAPK1TSHR | |
| SCHEMBL23772808 | 0.77 | LMNA (0.38) | KMT2AMEN1FAAHMAPK1TSHR | |
| SCHEMBL23772835 | 0.77 | FAAH (0.63) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL40805 | 0.76 | MEN1 (0.50) | KMT2AMEN1FAAHMAPK1TSHR | |
| SCHEMBL3313335 | 0.76 | MEN1 (0.50) | KMT2AMEN1FAAHMAPK1TSHR | |
| SCHEMBL27637631 | 0.76 | NPC1 (0.37) | KMT2AMEN1MAPK1TSHRCYP2C19 | |
| SCHEMBL15788961 | 0.76 | NPC1 (0.37) | KMT2AMEN1MAPK1TSHRCYP2C19 | |
| SCHEMBL7890623 | 0.73 | MEN1 (0.43) | KMT2AMEN1FAAHMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149264-B2 | Modified compounds and uses thereof | IONIS PHARMACEUTICALS, INC. (US) | 2021-10-19 | — | — | US | disclosed |