Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23923554 | 1.00 | GLA (0.51) | GLACTSLCTSSCTSKCTSB | |
| SCHEMBL23923394 | 0.91 | GPR139 (0.51) | GLACTSLCTSSCTSKGPR139 | |
| SCHEMBL23923396 | 0.91 | GPR139 (0.51) | GLACTSLCTSSCTSKGPR139 | |
| SCHEMBL23923365 | 0.88 | GPR139 (0.54) | CTSLCTSSCTSKCTSBGPR139 | |
| SCHEMBL23923367 | 0.88 | GPR139 (0.54) | CTSLCTSSCTSKCTSBGPR139 | |
| SCHEMBL23923528 | 0.88 | GPR139 (0.54) | GPR139PYGLRAB9AMMP9MMP8 | |
| SCHEMBL23923530 | 0.88 | GPR139 (0.54) | GPR139PYGLRAB9AMMP9MMP8 | |
| SCHEMBL23923341 | 0.85 | KMT2A (0.47) | CTSLCTSSCTSKCTSBGPR139 | |
| SCHEMBL23923343 | 0.85 | KMT2A (0.47) | CTSLCTSSCTSKCTSBGPR139 | |
| SCHEMBL23923324 | 0.84 | SLC6A9 (0.51) | CTSLCTSSCTSKGPR139PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11850247-B2 | Antiviral compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2023-12-26 | — | — | US | disclosed |
| US-20210322416-A1 | ANTIVIRAL COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-10-21 | — | — | US | disclosed |
| US-20210322416-A1 | ANTIVIRAL COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11850247-B2 | Antiviral compounds | ZC3HAV1, ZC3HAV1L, CD4 | GLA 2940/4885CTSL 1663/4885CTSS 858/4885 |
| US-20210322416-A1 | ANTIVIRAL COMPOUNDS | ZC3HAV1, ZC3HAV1L, CD4 | GLA 2940/4885CTSL 1663/4885CTSS 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.