SCHEMBL23924067

SCHEMBL23924067

CCS(=O)(=O)n1ccc(-c2cccc(OCc3ccccc3)c2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 1/20 0.48
BCHE P06276 2/20 0.46
LIPC P11150 1/20 0.46
ACHE P22303 1/20 0.46
LIPE Q05469 1/20 0.46
MAOB P27338 2/20 0.44
EGFR P00533 1/20 0.44
BRAF P15056 1/20 0.44
JAK3 P52333 1/20 0.44
MAPK10 P53779 1/20 0.44
KCNH2 Q12809 1/20 0.44
ERBB4 Q15303 1/20 0.44
NR1H4 Q96RI1 1/20 0.43
CHRNB2 P17787 3/20 0.43
CHRNB4 P30926 3/20 0.43
CHRNA3 P32297 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23951281 0.91 MAPT (0.56) MAPTCYP3A4CYP2C9CYP2C19HTT
SCHEMBL23951310 0.77 HSD17B2 (0.42) MAPTCYP3A4CYP2C9CYP2C19
SCHEMBL27753625 0.77 MAOB (0.44) BCHELIPCACHELIPEMAOB
SCHEMBL1385880 0.73 SDHB (0.49) MAPTCYP3A4CYP2C9CYP2C19HTT
SCHEMBL379281 0.72 MAOB (0.67) BCHEMAOBNR1H4MRGPRX4
SCHEMBL182623 0.70 NR4A2 (0.61) NR1H4MRGPRX4
SCHEMBL2137838 0.70 MRGPRX4 (0.69) BCHEMAOBMRGPRX4
SCHEMBL28225087 0.69 KMT2A (0.46) MAPTCYP3A4CYP2C9CYP2C19HTT
SCHEMBL31487931 0.69 MAOB (0.63) BCHEMAOB
SCHEMBL27635587 0.69 MAOB (0.63) BCHEMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12225904-B2 Phenylpyrazole compound and method for controlling plant disease SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-02-18 US disclosed
CN-112839505-B Phenylpyrazole compound and method for controlling plant disease 住友化学株式会社 2023-06-06 CN disclosed
US-20210321614-A1 PHENYLPYRAZOLE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-10-21 US disclosed
CN-112839505-A Phenylpyrazole compounds and method for controlling plant diseases 住友化学株式会社 2021-05-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12225904-B2 Phenylpyrazole compound and method for controlling plant disease HRH3, H1-3, HRH4 MAPT 2192/4885CYP3A4 218/4885CYP2C9 360/4885
US-20210321614-A1 PHENYLPYRAZOLE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE HRH3, H1-3, HRH4 MAPT 2192/4885CYP3A4 218/4885CYP2C9 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.