Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.69 |
| ▸ | AXL | P30530 | 1/20 | 0.69 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.69 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.69 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128811 | 0.81 | CYP19A1 (0.69) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL30098510 | 0.81 | CYP19A1 (0.69) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL6196239 | 0.81 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL3613262 | 0.81 | RAB9A (0.56) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL4656471 | 0.80 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL1807468 | 0.80 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL9571662 | 0.80 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| Bromide SCHEMBL15689048 | 0.80 | CYP19A1 (0.67) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL17014786 | 0.79 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL30128572 | 0.79 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878514-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115427394-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S.R.L. (IT) | 2022-07-07 | — | — | US | disclosed |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S R L (IT) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | CYP19A1 1508/4885AXL 3751/4885PBRM1 2301/4885 |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | CYP19A1 1508/4885AXL 3751/4885PBRM1 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.