Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276084 | 0.90 | ATM (0.49) | ATMSYKCTSLCTSBCTSS | |
| SCHEMBL1642417 | 0.87 | SYK (0.45) | ATMSYKCTSLCTSBCTSS | |
| SCHEMBL13413259 | 0.82 | SYK (0.48) | ATMSYKCTSLCTSBCTSS | |
| SCHEMBL13303244 | 0.80 | CTSL (0.48) | ATMCTSLCTSBCTSSELANE | |
| SCHEMBL2391974 | 0.80 | CTSL (0.48) | ATMCTSLCTSBCTSSELANE | |
| SCHEMBL2392485 | 0.79 | ATM (0.47) | ATMSYKCTSLCTSBCTSS | |
| SCHEMBL2501207 | 0.78 | ATM (0.47) | ATMCTSLCTSBCTSSELANE | |
| SCHEMBL3646006 | 0.77 | SYK (0.47) | ATMSYKCTSLCTSBCTSS | |
| SCHEMBL18157219 | 0.76 | ATM (0.53) | ATMSYKCTSLCTSBCTSS | |
| SCHEMBL30550771 | 0.76 | ATM (0.50) | ATMSYKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013008-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |