SCHEMBL23924910

SCHEMBL23924910

CC(=O)Nc1ccc(C)c(C)c1[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
LMNA P02545 4/20 0.46
ALDH1A1 P00352 5/20 0.44
HPGD P15428 2/20 0.44
HTT P42858 2/20 0.44
PKM P14618 3/20 0.42
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
GALR2 O43603 1/20 0.40
MITF O75030 1/20 0.40
HSP90AA1 P07900 1/20 0.40
XBP1 P17861 1/20 0.40
CCR6 P51684 1/20 0.40
MEN1 O00255 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10969677 0.87 KMT2A (0.47) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL11092141 0.85 KMT2A (0.49) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL5875056 0.83 KMT2A (0.47) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL23925201 0.81 KMT2A (0.52) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL5988015 0.80 SMN1; SMN2 (0.49) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL22032549 0.80 KMT2A (0.45) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL5563775 0.80 KMT2A (0.45) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL11620684 0.80 ALDH1A1 (0.58) KMT2AMAPTLMNAALDH1A1HPGD
SCHEMBL6579464 0.80 SMN1; SMN2 (0.43) KMT2AMAPTNPSR1LMNAALDH1A1
SCHEMBL7437123 0.80 KMT2A (0.44) KMT2AMAPTNPSR1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227657-A1 FLUORESCENT MACROMOLECULE AND USES THEREOF QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2023-07-20 US disclosed
US-20230227657-A1 FLUORESCENT MACROMOLECULE AND USES THEREOF QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2023-07-20 US disclosed
EP-4136126-A1 FLUORESCENT MACROMOLECULE AND USES THEREOF Queensland University Of Technology (AU) 2023-02-22 EP disclosed
CN-115427462-A Fluorescent macromolecules and uses thereof 昆士兰科技大学 2022-12-02 CN disclosed
WO-2021207793-A1 FLUORESCENT MACROMOLECULE AND USES THEREOF QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2021-10-21 WO disclosed
WO-2021207793-A1 FLUORESCENT MACROMOLECULE AND USES THEREOF QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2021-10-21 WO disclosed