SCHEMBL23925241

SCHEMBL23925241

NO[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.39
TSHR P16473 2/20 0.36
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL373264 1.00 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL10885691 1.00 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL21195733 0.84 TSHR (0.33) PDE4ATSHRCYP2C9
SCHEMBL21195712 0.84 TSHR (0.33) PDE4ATSHRCYP2C9
SCHEMBL6258700 0.79 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL645759 0.79 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL19384838 0.79 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL1143744 0.79 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL5029667 0.78 PDE4A (0.38) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL23923262 0.76 PDE4A (0.36) PDE4ATSHRCYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240102978-A1 IMPROVED METHOD FOR POLYSACCHARIDE QUANTIFICATION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-03-28 US disclosed
EP-4136443-A1 IMPROVED METHOD FOR POLYSACCHARIDE QUANTIFICATION GlaxoSmithKline Biologicals S.A. (BE) 2023-02-22 EP disclosed
CN-115667914-A Improved method for polysaccharide quantification 葛兰素史密丝克莱恩生物有限公司 2023-01-31 CN disclosed
WO-2021209353-A1 IMPROVED METHOD FOR POLYSACCHARIDE QUANTIFICATION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2021-10-21 WO disclosed