SCHEMBL645759

SCHEMBL645759

CO[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.39
TSHR P16473 2/20 0.36
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PGD P52209 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1143744 1.00 PDE4A (0.39) PDE4ATSHRSLC1A3SLC1A2SLC1A1
SCHEMBL570718 0.84 TSHR (0.33) TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL5458333 0.84 TSHR (0.33) PDE4ATSHRSLC1A3SLC1A2SLC1A1
SCHEMBL7148889 0.84 TSHR (0.33) TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL23923262 0.80 PDE4A (0.36) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL1037497 0.80 PDE4A (0.36) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL1950299 0.80 PDE4A (0.36) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL6258700 0.79 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL10885691 0.79 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1
SCHEMBL23925241 0.79 PDE4A (0.39) PDE4ATSHRCYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4157853-B1 GUT MICROBIOTA BIOACTIVATED PDE4 INHIBITOR PRECURSORS GIIANT PHARMA INC (CA) 2024-07-31 EP claimed
CN-118304193-A External cream capable of preventing female climacteric symptoms 珠海众赫生物技术有限公司 2024-07-09 CN claimed
WO-2019104213-A1 ANTIBIOFILM FORMULATIONS AND USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-05-31 WO claimed
EP-2971254-B1 METHODS FOR THE ELECTROLYTIC DECARBOXYLATION OF SUGARS DYNAMIC FOOD INGREDIENTS CORP (US) 2019-02-20 EP claimed
CN-104080355-B Chewing gum base containing substituted polysaccharide and the chewing gum product being produced from it WM.雷格利 JR.公司 2018-05-29 CN claimed
US-20160289719-A1 MODIFICATION OF THE XYLAN UTILIZATION SYSTEM FOR PRODUCTION OF ACIDIC XYLOOLIGOSACCHARIDES FROM LIGNOCELLULOSICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2016-10-06 US claimed
WO-2015077744-A1 MODIFICATION OF THE XYLAN UTILIZATION SYSTEM FOR PRODUCTION OF ACIDIC XYLOOLIGOSACCHARIDES FROM LIGNOCELLULOSICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INCORPORATED (US) 2015-05-28 WO claimed
US-20100152435-A1 COMPOSITIONS AND PROCESSES FOR THE SELECTIVE CATALYTIC OXIDATION OF ALCOHOLS STAPLEY JONATHAN A 2010-06-17 US claimed
WO-2008113028-A1 COMPOSITIONS AND PROCESSES FOR THE SELECTIVE CATALYTIC OXIDATION OF ALCOHOLS DYNAMIC FOOD INGREDIENTS CORPORATION (US) 2008-09-18 WO claimed
US-20030037893-A1 Electrophotographic paper and method for manufacturing thereof OY KESKUSLABORATORIO - OY CENTRALLABORATORIUM AB (FI) 2003-02-27 US claimed
EP-1272904-A1 ELECTROPHOTOGRAPHIC PAPER AND METHOD FOR MANUFACTURING THEREOF OY KESKUSLABORATORIO - CENTRALLABORATORIUM AB (FI) 2003-01-08 EP claimed
WO-2001075527-A1 ELECTROPHOTOGRAPHIC PAPER AND METHOD FOR MANUFACTURING THEREOF OY KESKUSLABORATORIO - CENTRALLABORATORIUM AB (FI) 2001-10-11 WO claimed
EP-0511917-B1 Glycosylated prodrugs, process for their preparation and uses thereof HOECHST SA LAB (FR) 1996-10-23 EP claimed
CN-116284503-B Xylan and preparation method and application thereof 苏州融析生物科技有限公司 2025-05-16 CN disclosed
CN-119947692-A Gel composition and oil-in-water composition 株式会社资生堂 2025-05-06 CN disclosed
US-12127577-B2 Compositions rich in arabinoxylan oligosaccharides PURATOS N.V. (BE) 2024-10-29 US disclosed
EP-0615564-A1 METHOD AND ENZYMATIC PREPARATION FOR TREATMENT OF CELLULOSE PULPS VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 1994-09-21 EP disclosed
EP-0607243-A1 METHOD FOR ENZYMATIC TREATMENT OF LIGNOCELLULOSIC MATERIALS, IN PARTICULAR CELLULOSE PULPS VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 1994-07-27 EP disclosed
WO-1993011296-A1 METHOD AND ENZYMATIC PREPARATION FOR TREATMENT OF CELLULOSE PULPS VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 1993-06-10 WO disclosed
WO-1993007332-A1 METHOD FOR ENZYMATIC TREATMENT OF LIGNOCELLULOSIC MATERIALS, IN PARTICULAR CELLULOSE PULPS VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 1993-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152435-A1 COMPOSITIONS AND PROCESSES FOR THE SELECTIVE CATALYTIC OXIDATION OF ALCOHOLS ADH1C, UGGT1, ADH1A PDE4A 2231/4885TSHR 3052/4885SLC1A3 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.