Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ4 | P56696 | 3/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663681 | 0.85 | HDAC6 (0.34) | KCNQ4KCNQ5CA14HDAC1HDAC2 | |
| SCHEMBL15268917 | 0.85 | AKT1 (0.40) | KCNQ4KCNQ5CA14 | |
| SCHEMBL22619240 | 0.77 | CA14 (0.41) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL1207293 | 0.73 | CA14 (0.39) | KCNQ4KCNQ5CA14HDAC1HDAC2 | |
| SCHEMBL6692478 | 0.73 | HDAC6 (0.36) | KCNQ4KCNQ5CA14HDAC1HDAC2 | |
| SCHEMBL20029121 | 0.72 | CA14 (0.34) | KCNQ4KCNQ5CA14HDAC1HDAC2 | |
| SCHEMBL23925352 | 0.72 | HDAC6 (0.34) | KCNQ4KCNQ5HDAC1HDAC2HDAC6 | |
| SCHEMBL1743767 | 0.72 | HDAC6 (0.35) | KCNQ4KCNQ5CA14HDAC1HDAC2 | |
| SCHEMBL30897721 | 0.70 | HDAC6 (0.34) | KCNQ4KCNQ5CA14HDAC1HDAC2 | |
| SCHEMBL1696194 | 0.70 | HDAC6 (0.35) | KCNQ4KCNQ5HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174965-A1 | METHODS AND PRODUCTS | UNIV BIRMINGHAM (GB) | 2023-06-08 | — | — | US | disclosed |
| EP-4136223-A2 | METHODS AND PRODUCTS | The University Of Birmingham (GB) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021209765-A2 | METHODS AND PRODUCTS | THE UNIVERSITY OF BIRMINGHAM (GB) | 2021-10-21 | — | — | WO | disclosed |