Xylose

Xylose

SCHEMBL23925306

NC(=O)c1cccnc1.O=CC(O)C(O)C(O)CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.58
F3 P13726 1/20 0.58
SARM1 Q6SZW1 1/20 0.58
SIRT2 Q8IXJ6 1/20 0.58
SIRT6 Q8N6T7 1/20 0.58
SIRT1 Q96EB6 1/20 0.58
SIRT3 Q9NTG7 1/20 0.58
SIRT5 Q9NXA8 1/20 0.58
SIRT4 Q9Y6E7 1/20 0.58
MKNK1 Q9BUB5 2/20 0.41
MKNK2 Q9HBH9 2/20 0.41
THRB P10828 1/20 0.41
ALDH1A1 P00352 4/20 0.41
APP P05067 1/20 0.41
GAA P10253 1/20 0.41
HCAR3 P49019 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
PLOD2 O00469 1/20 0.39
TBXAS1 P24557 3/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xylose SCHEMBL938610 1.00 F7 (0.58) F7F3SARM1SIRT2SIRT6
Xylose SCHEMBL20423632 0.99 F7 (0.56) F7F3SARM1SIRT2SIRT6
Xylose SCHEMBL28724079 0.99 F7 (0.56) F7F3SARM1SIRT2SIRT6
Demannose SCHEMBL27666893 0.96 F7 (0.56) F7F3SARM1SIRT2SIRT6
Xylose SCHEMBL23706155 0.95 F7 (0.52) F7F3SARM1SIRT2SIRT6
Xylose SCHEMBL28825332 0.94 F7 (0.51) F7F3SARM1SIRT2SIRT6
Cadaverine Tartrate SCHEMBL28825318 0.94 F7 (0.51) F7F3SARM1SIRT2SIRT6
Xylose SCHEMBL4484244 0.91 SIRT2 (0.48) F7F3SARM1SIRT2SIRT6
Xylose SCHEMBL28724080 0.90 F7 (0.47) F7F3SARM1SIRT2SIRT6
Mannitol SCHEMBL9807801 0.89 F7 (0.69) F7F3SARM1SIRT2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024164494-A1 GLYCERIC ACID, GLYCERATE, AND COMPOSITION THEREOF Inner Mongolia Kingdomway Pharmaceutical Co., Ltd. (CN) 2024-08-15 WO claimed
CN-109717474-A A kind of weight losing meal-replacing powder and preparation method thereof with stomach nourition, and beauty treatment function 天津天狮生物发展有限公司 2019-05-07 CN claimed
CN-109350622-A The group technology of niacinamide core carbohydrates and their derivative and pyrroloquinoline quinone and its sodium salt 深圳市龙格生技术有限公司 2019-02-19 CN claimed
CN-121489969-A Anti-aging composition 金斯立德(深圳)生物技术有限公司 2026-02-10 CN disclosed
CN-118048336-A Multifunctional catalytic enzyme, mutant, polynucleotide, recombinant expression vector, preparation method and application thereof 上海交通大学 2024-05-17 CN disclosed
CN-117752643-A Use of metformin or nicotinamide riboside 中国科学院动物研究所 2024-03-26 CN disclosed
CN-219092003-U System for recovering alkali metal adenosine triphosphate and system for preparing beta-nicotinamide mononucleotide 湖北远大生命科学与技术有限责任公司 2023-05-30 CN disclosed
CN-115867289-A Composition containing NR and/or NMN and sesamin 三得利控股株式会社 2023-03-28 CN disclosed
CN-115843295-A NAMPT modulators 赛特凯恩蒂克公司 2023-03-24 CN disclosed
CN-115820768-A Method for producing beta-nicotinamide mononucleotide by utilizing multienzyme cyclic cascade strategy 河南师范大学 2023-03-21 CN disclosed
CN-114716343-B Novel NAMPT enzyme agonist, preparation and application thereof 清华大学 2023-03-21 CN disclosed
CN-115197126-A Novel NMNAT enzyme agonist and preparation and application thereof 清华大学 2022-10-18 CN disclosed
CN-114990088-A Nicotinamide ribokinase mutant and preparation method of recombinant bacterium and NMN thereof 中食都庆(山东)生物技术有限公司 2022-09-02 CN disclosed
CN-112094362-B Nicotinamide ribose or mononucleotide analogue-macromolecular carrier conjugate, preparation method and application 四川大学华西医院 2022-04-12 CN disclosed
WO-2021253476-A1 METHOD FOR SYNTHESIZING BETA-NICOTINAMIDE MONONUCLEOTIDE AND INTERMEDIATE THEREOF 理星(天津)生物科技有限公司 2021-12-23 WO disclosed
WO-2021209998-A1 COMPOSITION FOR THE TREATMENT OF RESPIRATORY SYMPTOMS AND METHODS THEREOF MOLAD AMI (IL) 2021-10-21 WO disclosed
CN-112094362-A Nicotinamide ribose or mononucleotide analogue-macromolecular carrier conjugate, preparation method and application 四川大学华西医院 2020-12-18 CN disclosed
CN-103570725-B Piperazidinoltriazole compound as well as preparation method and application thereof 中国科学院上海药物研究所 2017-03-22 CN disclosed
CN-103833756-B One-class pyridazinone compounds and its production and use 中国科学院上海药物研究所 2016-12-21 CN disclosed
CN-101945999-B Stabilization of dehydrogenases with stabilized coenzymes 霍夫曼-拉罗奇有限公司 2016-06-08 CN disclosed