Known targets — ChEMBL curated mechanism
ADRB1ADRB2ATP4AATP4BAXLCHRM2CHRM3DRD2FLT3HRH1HTR2AHTR2BHTR2CKCNH2KMT2AMAP2K1MAP2K2MEN1MLNRPLK4RENS1PR1SLC6A2SLC6A4atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Xylose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.51 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xylose SCHEMBL938610 | 0.94 | F7 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| Xylose SCHEMBL23925306 | 0.94 | F7 (0.58) | F7F3SARM1SIRT2SIRT6 | |
| Xylose SCHEMBL28724079 | 0.93 | F7 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| Xylose SCHEMBL20423632 | 0.93 | F7 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| Cadaverine Tartrate SCHEMBL28825318 | 0.91 | F7 (0.51) | F7F3SARM1SIRT2SIRT6 | |
| Demannose SCHEMBL27666893 | 0.90 | F7 (0.56) | F7F3SARM1SIRT2SIRT6 | |
| Xylose SCHEMBL23706155 | 0.89 | F7 (0.52) | F7F3SARM1SIRT2SIRT6 | |
| Xylose SCHEMBL4484244 | 0.85 | SIRT2 (0.48) | F7F3SARM1SIRT2SIRT6 | |
| Xylose SCHEMBL27986605 | 0.85 | ALDH1A1 (0.57) | F7F3SARM1SIRT2SIRT6 | |
| Citric Acid SCHEMBL28825296 | 0.85 | F7 (0.45) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933621-A | Organic acid salt of nicotinamide ribose, and crystal form, preparation method and application thereof | 深圳市迪克曼生物科技有限公司 | 2022-08-23 | — | — | CN | disclosed |