Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | AMD1 | P17707 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335682 | 0.91 | NUDT1 (0.54) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL2392109 | 0.89 | HSP90AA1 (0.50) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL8634483 | 0.87 | NUDT1 (0.73) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL8626519 | 0.87 | KMT2A (0.46) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL10618273 | 0.84 | NUDT1 (0.44) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL16488336 | 0.79 | CYP2C19 (0.42) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL29154 | 0.79 | NUDT1 (0.69) | NUDT1ALDH1A1MAPTL3MBTL1HSP90AA1 | |
| SCHEMBL29625490 | 0.79 | NUDT1 (0.69) | NUDT1ALDH1A1MAPTL3MBTL1HSP90AA1 | |
| SCHEMBL25011788 | 0.76 | MAPT (0.37) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL20606959 | 0.76 | MAPT (0.50) | NUDT1CYP1A2CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195302-B1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-2195302-B1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-02-18 | — | — | EP | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| EP-2195302-A2 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | Dow AgroSciences LLC (US) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009048752-A2 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-16 | — | — | WO | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | NUDT1 605/4885CYP1A2 908/4885CYP2C19 1325/4885 |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | NUDT1 605/4885CYP1A2 908/4885CYP2C19 1325/4885 |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | NUDT1 605/4885CYP1A2 908/4885CYP2C19 1325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.