Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392582 | 0.87 | NUDT1 (0.53) | KMT2ANUDT1MEN1SMN1; SMN2CYP2C19 | |
| SCHEMBL10618273 | 0.83 | NUDT1 (0.44) | KMT2ANUDT1MEN1CYP2C19CYP1A2 | |
| SCHEMBL20606959 | 0.83 | MAPT (0.50) | KMT2ANUDT1MEN1SMN1; SMN2CYP2C19 | |
| SCHEMBL2392109 | 0.81 | HSP90AA1 (0.50) | KMT2ANUDT1MEN1CYP2C19CYP1A2 | |
| SCHEMBL6335682 | 0.79 | NUDT1 (0.54) | KMT2ANUDT1MEN1CYP2C19CYP1A2 | |
| SCHEMBL8634483 | 0.79 | NUDT1 (0.73) | KMT2ANUDT1MEN1SMN1; SMN2CYP2C19 | |
| SCHEMBL30931677 | 0.77 | LOXL2 (0.40) | KMT2ANUDT1MEN1CYP2C19CYP1A2 | |
| SCHEMBL7808650 | 0.77 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL1576783 | 0.77 | SMN1; SMN2 (0.55) | KMT2ANUDT1MEN1SMN1; SMN2CYP2C19 | |
| SCHEMBL14857458 | 0.76 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5696257-A | INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |