Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798278 | 0.83 | SCN9A (0.61) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL22798280 | 0.83 | SCN9A (0.61) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL20595160 | 0.82 | SCN9A (0.62) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL20595161 | 0.82 | SCN9A (0.62) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL28354862 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL15731331 | 0.80 | SCN9A (0.47) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL8771848 | 0.78 | KDM4E (0.44) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL13046537 | 0.77 | LMNA (0.42) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL28354400 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL22798207 | 0.76 | SCN9A (0.63) | ALDH1A1KMT2AKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | RAQUALIA PHARMA INC. (JP) | 2021-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | SCN8A, SCN7A, SCN1A | ALDH1A1 2581/4885KMT2A 1799/4885MEN1 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.