SCHEMBL23926331

SCHEMBL23926331

Cc1ccc(OCc2ccccc2)c(C(=O)C2CCCN2C(=O)O)n1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
APP P05067 5/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HCRTR1 O43613 1/20 0.42
HCRTR2 O43614 1/20 0.42
SPHK2 Q9NRA0 1/20 0.42
SPHK1 Q9NYA1 1/20 0.42
FKBP1A P62942 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PREP P48147 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23926332 0.96 APP (0.44) MEN1KMT2AAPPTP53FKBP1A
SCHEMBL30118914 0.88 KLK7 (0.52) MEN1KMT2ATP53TSHRL3MBTL1
SCHEMBL23926370 0.88 KLK7 (0.52) MEN1KMT2ATP53TSHRL3MBTL1
SCHEMBL23926339 0.88 SPHK2 (0.42) MEN1KMT2AAPPTSHRL3MBTL1
SCHEMBL30118942 0.88 SPHK2 (0.42) MEN1KMT2AAPPTSHRL3MBTL1
SCHEMBL24127946 0.86 KLK7 (0.49) MEN1KMT2AAPPTSHRL3MBTL1
SCHEMBL30118945 0.85 KLK7 (0.49) MEN1KMT2AAPPTSHRL3MBTL1
SCHEMBL23964598 0.85 KLK7 (0.49) MEN1KMT2AAPPTSHRL3MBTL1
SCHEMBL23926327 0.84 SPHK2 (0.41) APPHCRTR1HCRTR2SPHK2SPHK1
SCHEMBL30118961 0.84 SPHK2 (0.41) APPHCRTR1HCRTR2SPHK2SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155547-B1 Compounds for and methods of treating diseases Alterity Therapeutics Limited (AU) 2021-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11155547-B1 Compounds for and methods of treating diseases HTT, SNCA, PARK7 MEN1 1161/4885KMT2A 730/4885APP 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.